
Prolotherapy ("Proliferative Injection Therapy") involves injecting an otherwise non-pharmacological and non-active irritant solution into the body, generally in the region of tendons or ligaments for the purpose of strengthening weakened connective tissue and alleviating musculoskeletal pain. Dozens of studies show benefits of prolotherapy for people with chronic pain, as well as those with sports injuries. Many solutions are used, including Dextrose, Lidocaine (a commonly used local anesthetic), Phenol (an alcohol), Glycerine, or Cod Liver Oil extract. Other compounds, known as growth factors, can also be added to the injection solution. The prototypical growth factor is Human Growth Hormone (HGH) which can be used in certain prolotherapy injections to help stimulate tissue repair and regeneration. Most notably, HGH/Prolotherapy injections can useful in osteoarthritis of the knee, and ankle.
Prolotherapy injections are given into joints, or where tendon connects to bone. Many points may require injection. The Injected solution causes the body to heal itself through the process of inflammation and repair. In the case of weakened or torn connective tissue, induced inflammation and release of growth factor at the site of injury may result in a 30-40% strengthening of the attachment points.
Prolotherapy sessions are generally given every 1-2 weeks, and the initial treatment cycle usually needs about 6 sessions. After that, many patients receive treatment at less and less frequent intervals until treatments are required only every several years, if at all. Side effects are minimal, and may include some transient stiffness/aching in the injected area(s), but this typically passes quickly.
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Thank you so much for restoring the gift of running to me. After visiting several doctors over the years, no one could figure out what was exactly wrong. I finally went to SEMI, and was diagnosed with tendonitis, bursitis and a heel spur, and was told that surgery would be needed to fix the problem. The surgery was performed successfully in September 2002. In December 2003 I went on to win the age group title at Canadian cross-country championships. Thank you.
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